- PhD: North Carolina State University at Raleigh.
- Kollitz EM, Hawkins MB, Whitfield GK, Kullman SW. Functional Diversification of Vitamin D Receptor Paralogs in Teleost Fish After a Whole Genome Duplication Event. Endocrinology. 2014 155(12):4641-4654. PMID: 25279795.
- Austin HR, Hoss E, Batie SF, Moffet EW, Jurutka PW, Haussler MR, Whitfield GK. Regulation of late cornified envelope genes relevant to psoriasis risk by plant-derived cyanidin. Biochem Biophys Res Commun. 2014 443(4):1275-9. PMID: 24393842.
- Hoss E, Austin HR, Batie SF, Jurutka PW, Haussler MR, Whitfield GK. Control of late cornified envelope genes relevant to psoriasis risk: upregulation by 1,25-dihydroxyvitamin D3 and plant-derived delphinidin. Arch Dermatol Res. 2013 305(10):867-78. PMID: 23839497.
- Hsieh JC, Slater SA, Whitfield GK, Dawson JL, Hsieh G, Sheedy C, Haussler CA, Haussler MR. Analysis of hairless corepressor mutants to characterize molecular cooperation with the vitamin D receptor in promoting the mammalian hair cycle. J Cell Biochem. 2010 110(3):671-686.
- Haussler MR, Haussler CA, Whitfield GK, Hsieh JC, Thompson PD, Barthel TK, Bartik L, Egan JB, Wu Y, Kubicek JL, Lowmiller CL, Moffet EW, Forster RE, Jurutka PW. The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the "Fountain of Youth" to mediate healthful aging. J Steroid Biochem Mol Biol. 2010 121(1-2):88-97.
For a complete listing of Dr. Whitfield's publications, search PubMed.
Bone, skin and mucosal disease; Developmental, cell and molecular biology; Gene environment interactions and epigenetics; Signaling and steroid biology
Research by Dr. Whitfield focuses on elucidating the role of the mammalian vitamin D receptor (VDR) in treating psoriasis, for which VDR ligands are an approved therapy. In addition to 1,25-dihydroxyvitamin D (1,25D), other compounds under investigation include delphinidin, cyanidin and resveratrol. Identifying which psoriasis-relevant genes are regulated by VDR in skin could lead to superior agents to treat mild/moderate psoriasis for which there is currently no satisfactory therapy.