Dr. Shenfeng Qiu, PhD head shot

Contact Info

Phone:
602-827-2173
Fax #:
602-827-2130

Associate Professor

Faculty
College of Medicine Phx Basic Medical Sciences

Lab Website

Education

  • Postdoctoral: Neurodevelopmental Disorders, Vanderbilt University, 2004 – 2012.
  • PhD: University of California, Riverside, 2004.
  • MD: Nanjing Medical University, China, 1994.

Publications

  • Qiu S*, Lu Z and Levitt P. MET receptor tyrosine kinase controls dendritic complexity, spine morphogenesis, and glutamatergic synapse maturation in the hippocampus". The Journal of Neuroscience. 2014,34(49):16166-79.
  • Peng Y*, Lu Z*, Li G, Piechowicz M, Anderson M, Uddin Y, Wu J and Qiu S. The autism associated MET receptor tyrosine kinase engages early neuronal growth mechanism and controls glutamatergic circuits development in the forebrain. Molecular Psychiatry. *equal contribution. [Cover article]. 2016 Jan 5. Online.
  • Aldinger KA, Plummer JT, Qiu S, Levitt P. SnapShot: Genetics of Autism.Neuron, 2011; 72 (2):418-418.e1.
  • Qiu S*, Anderson CT*, Levitt P and Shepherd GM. Circuit-specific intracortical hyperconnectivity in mice with deletion of the autism-associated Met receptor tyrosine kinase. (*joint first author). J Neurosci, 2011; 31(15):5855-64.
  • Qiu S, ChampagneDL, Peters M, Weeber EJ, Levitt P and Pimenta A. Loss of limbic system-associated membrane protein leads to reduced hippocampal mineralocorticoidreceptor expression, impaired synaptic plasticity and spatialmemory deficit. Biological Psychiatry, 2010; 68(2):197-204.

*Correspondent author

For a complete listing of Dr. Qui's publications, search PubMed.

Research Interests

Neurodevelopmental disorders, brain circuits, electrophysiology

Research Summary

The overall interest of Dr. Shenfeng Qiu's lab is to understand the brain origins of neurodevelopmental and neuropsychiatric disorders, such as autism spectrum disorders. One ongoing project (R01MH111619) focuses on the role of MET tyrosine kinase, identified as a major risk for autism. Our lab aims to identify mechanisms by which MET affects neuronal growth, maturation and brain circuit function. We are also interested in the UBE3A protein in Angelman syndrome. Together with Ferguson lab, we also explore distinct brain circuits mediating anxiety and depression (R21MH113679).