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Associate Professor

College of Medicine Phx Basic Medical Sciences

Research Interests

Neurodegenerative, developmental and psychiatric disease; developmental, cell and molecular biology; signaling and steroid biology

Research Summary

The Sattler laboratory studies cellular and molecular mechanisms of neurodegeneration in CNS disorders including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) with a particular interest in the role of synaptic dysfunction. We utilize different disease models including patient-derived human induced pluripotent stem cells, patient autopsy brain tissue and animal models of disease and employ state of the art molecular, biochemical and microscopy technologies.