Contact:
University of Arizona College of Medicine - Phoenix 425 North 5th Street, Phoenix, AZ 85004
Associate Professor, N/A
Associate Professor, Tenure - Basic Medical Sciences
Associate Professor, N/A - Translational Neurosciences
Undergraduate Medical Education
Faculty
Basic Medical Sciences; Translational Neurosciences; Undergraduate Medical Education
Education
- Postdoctoral Fellowship: Cerebrovascular Physiology, 2005
- PhD: Vascular Biology, University of New Mexico, School of Medicine, 1999
Publications
- K Arkelius, Wendt T, Andersson H, Arnou A, Gottschalk M, Gonzales RJ & Ansar S (2024). LOX-1 and MMP-9 Inhibition Attenuates the Detrimental Effects of Delayed rt-PA Therapy and Improves Outcomes After Acute Ischemic Stroke. Circulation Research., 04/12/2024 - Article, Refereed Journal -
- Wendt T & Gonzales RJ (2023). Ozanimod differentially preserves human cerebrovascular endothelial barrier proteins and attenuates matrix metalloproteinase-9 activity following in vitro acute ischemic injury. AJP Cell Physiology., 08/29/2023 - Article, Refereed Journal -
- Wendt T, Li YL & Gonzales RJ (2021). Ozanimod, an S1PR1 ligand, attenuates hypoxia plus glucose deprivation induced autophagic flux and phenotypic switching in human brain VSM cells. AJP Cell Physiology., 03/31/2021 - Article, Refereed Journal -
- Li Y, Shi SX, Liu Q, Shi FD & Gonzales RJ (2020). Targeted role for S1PR in endothelial function, neuroinflammation and neurovascular dysfunction during ischemic stroke. Neurosci Lett. Vol. 735, 09/14/2020 - Article, Refereed Journal -
- Li H, Zhou X, Li Y, Ma X, Gonzales RJ, Qiu S, Shi FD & Liu Q (2019). The selective sphingosine 1-phosphate receptor 1 modulator RP101075 improves microvascular circulation after cerebrovascular thrombosis. FASEB J. Vol. 33(10), 10935-10941., 10/2019 - Article, Refereed Journal -
- Jin WN, Gonzales RJ, Feng Y, Wood K, Chai Z, Dong JF, La Cava A, Shi FD & Liu Q (2018). Brain ischemia induces diversified neuroantigen-specific T-cell responses that exacerbate brain injury. Stroke. Vol. 49(6), 1471-1478., 06/2018 - Article, Refereed Journal -
- Raman P, Madhavpeddi L & Gonzales RJ (2018). Palmitate induces glycosylation of cyclooxygenase-2 in primary human vascular smooth muscle cells. Am J Physiol Cell Physiol. Vol. 314(5), C545-C553., 05/01/2018 - Article, Refereed Journal -
- Jin WN, Ducruet AF, Liu Q, Shi SX, Waters M, Zou M, Sheth KN, Gonzales RJ & Shi FD (2018). Activation of JAK/STAT3 restores NK-cell function and improves immune defense after brain ischemia. FASEB J. Vol. 32(5), 2757-2767., 05/2018 - Article, Refereed Journal -
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Research Interests
- Vascular Inflammation - Vascular Biology - Stroke - Psychiatric Disease - Neurodegenerative Diseases - Cerebrovascular Disorders - Cell signaling - Cardiovascular Diseases - Cardiovascular Biology