Students are instructed and can choose elective rotations at the Scottsdale branch of the renowned Mayo Clinic. Mayo Clinic's Arizona campus is ranked the No. 1 hospital in Arizona by U.S. News & World Report and is ranked No. 11 in the nation on the "Best Hospitals Honor Roll.” The clinical practice is focused on adult specialty and surgical care in more than 65 medical and surgical disciplines, supported by outstanding programs in medical education and research. 

The Scottsdale campus, which opened in 1987, includes the Mayo Clinic Building, the Samuel C. Johnson Research Building and the Mayo Clinic Collaborative Research Building.