Contact:
University of Arizona College of Medicine - Phoenix 425 North 5th Street, Phoenix, AZ 85004
Professor, N/A
Professor, Tenure - Basic Medical Sciences
Professor, N/A - Psychiatry
Professor, N/A - Translational Neurosciences
Faculty
Basic Medical Sciences; Psychiatry; Translational Neurosciences
Education
- Postdoctoral Fellowship: Molecular Neuroscience and Psychiatric Genetics, Washington University in St. Louis, 2003
- Residency: Psychiatry, Columbia University, The New York State Psychiatric Institute, 2001
- MD, PhD: Neuroscience, University of Pennsylvania, School of Medicine, 1997
Publications
- Marballi KK, Alganem K, Brunwasser SJ, Barkatullah A, Meyers KT, Campbell JM, Ozols AB, Mccullumsmith R & Gallitano AL (2022). Identification of activity-induced Egr3-dependent genes reveals genes associated with DNA damage response and schizophrenia. Transl Psychiatry. Vol. 12, 08/08/2022 - Article, Refereed Journal -
- Zhao X, Ozols AB, Meyers KT, Campbell J, McBride A, Marballi KK, Maple AM, Raskin C, Mishra A, Noss S, Beck KL, Khoshaba R, Bhaskara A, Godbole MN, Lish J, Kang P, Hu C, Palner M, Overgaard A, Knudsen GM & Gallitano AL (2022). Acute sleep deprivation upregulates serotonin 2A receptors in the frontal cortex of mice via the immediate early gene Egr3. Mol Psychiatry. Vol. 27, 03/2022 - Article, Refereed Journal -
- Gallitano AL (2020). The Role of Immediate Early Genes in Neuropsychiatric Illness. Front Behav Neurosci. Vol. 14, 16., 02/21/2020 - Editorial -
- Zhao X, Meyers KT, Marballi KK, Maple AM, Kang P, Palner M, Overgaard A, Knudsen GM & Gallitano AL (2019). Environment Rapidly Upregulates Serotonin 2A Receptor Expression via Immediate Early Gene Egr3. BioRxiv., 05/10/2019 - Article, Refereed Journal -
- Maple AM, Rowe RK, Lifshitz J, Fernandez F & Gallitano AL (2018). Influence of Schizophrenia-Associated Gene Egr3 on Sleep Behavior and Circadian Rhythms in Mice. J Biol Rhythms. Vol. 33(6), 662-670., 12/2018 - Article, Refereed Journal -
Specialties
- American Board of Psychiatry and Neurology
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Research Interests
- Schizophrenia - Psychiatric Disease - Neurodegenerative Diseases - Gene-Environment Interaction - Developmental, cell and molecular biology - Developmental Disabilities - Cell signaling
Research Summary
The Gallitano Lab investigates the molecular mechanisms underlying the dual genetic and environmental risk for neuropsychiatric illnesses such as schizophrenia and mood disorders. We focus on immediate early genes that are activated in the brain by environmental stimuli, including stress, and regulate processes disrupted in mental illnesses. Ongoing studies examine how Egr3 regulates effectors including Arc and the serotonin 2A receptor to influence synaptic plasticity, memory, and behavior.