Amelia L. Gallitano-Mendel

Contact:

University of Arizona College of Medicine - Phoenix ABC-1 Building 425 North 5th Street, Phoenix, AZ 85004
Building
AZ Biomedical Collaborative 1
Professor & Director, Women in Medicine & Science, Office of Equity, Diversity & Inclusion
Professor - Basic Medical Sciences
Professor - Psychiatry
Director, Women in Medicine & Science, Office of Equity, Diversity & Inclusion
Faculty
Basic Medical Sciences; Psychiatry

Education

  • Postdoctoral Fellowship: Molecular Neuroscience and Psychiatric Genetics, Washington University in St Louis, 2003
  • Residency: Psychiatry, Columbia University in the City of New York, The New York State Psychiatric Institute, 2001
  • Internship: Psychiatry, Columbia University in the City of New York, The New York State Psychiatric Institute, 2001
  • MD, PhD: Neuroscience, University of Pennsylvania, School of Medicine, 1997

Specialties

  • American Board of Psychiatry and Neurology

Representative Recent Publications

  • Gallitano AL (2020). The Role of Immediate Early Genes in Neuropsychiatric Illness. Front Behav Neurosci. Vol. 14, 16.
  • Zhao X, Meyers KT, Marballi KK, Maple AM, Kang P, Palner M, Overgaard A, Knudsen GM & Gallitano AL (2019). Environment Rapidly Upregulates Serotonin 2A Receptor Expression via Immediate Early Gene Egr3. BioRxiv.
  • Maple AM, Rowe RK, Lifshitz J, Fernandez F & Gallitano AL (2018). Influence of Schizophrenia-Associated Gene Egr3 on Sleep Behavior and Circadian Rhythms in Mice. J Biol Rhythms. Vol. 33(6), 662-670.
  • Meyers KT, Marballi KK, Brunwasser SJ, Renda B, Charbel M, Marrone DF & Gallitano AL (2018). The Immediate Early Gene Egr3 Is Required for Hippocampal Induction of Bdnf by Electroconvulsive Stimulation. Front Behav Neurosci. Vol. 12, 92.
  • Marballi KK & Gallitano AL (2018). Immediate Early Genes Anchor a Biological Pathway of Proteins Required for Memory Formation, Long-Term Depression and Risk for Schizophrenia. Front Behav Neurosci. Vol. 12, 23.
Research Interests
Schizophrenia, Psychiatric Disease, Neurodegenerative Diseases, Gene-Environment Interaction, Developmental, cell and molecular biology, Developmental Disabilities, Cell signaling
Research Summary
The Gallitano Lab investigates the molecular mechanisms underlying the dual genetic and environmental risk for neuropsychiatric illnesses such as schizophrenia and mood disorders. We focus on immediate early genes that are activated in the brain by environmental stimuli, including stress, and regulate processes disrupted in mental illnesses. Ongoing studies examine how Egr3 regulates effectors including Arc and the serotonin 2A receptor to influence synaptic plasticity, memory, and behavior.