Dr. Kurt Gustin, PhD head shot

Contact Info

Building
AZ Biomedical Collaborative 1
Room Number
328
Associate Professor
Faculty
College of Medicine Phx Basic Medical Sciences

Education

  • Post-Doctoral: Virology and Cell Biology, Stanford University, 1998 – 2004.
  • PhD: University of Michigan, 1998.

Publications

  • Ke H, Han M, Kim J, Gustin KE and D. Yoo. Porcine Reproductive and Respiratory Syndrome Virus nsp1-beta Protein Interacts with Nucleoporin 62 (Nup62) to Promote Viral Replication and Immune Evasion. Journal of Virology, 2019. 93:e00469-19.
  • Kotla S and Gustin KE. Proteolysis of MDA5 and IPS-1 is Not Required for Inhibition of the Type I IFN Response by Poliovirus. Virology Journal, 2015. 12:158.
  • Park N, Schweers NJ and Gustin KE. Selective Removal Of FG-Repeat Domains From The Nuclear Pore Complex By Enterovirus 2Apro. Journal of Virology, 2015. 89:11069-79.
  • Pathak A, Adams RH, Shah NC and Gustin KE. Persistent human rhinovirus type C infection of the lower respiratory tract in a pediatric cord blood transplant recipient. Bone Marrow Transplantation, 2013. 48:747-8.
  • Park N, Skern T and Gustin KE. Specific Cleavage of the Nuclear Pore Complex Protein Nup62 by a Viral Protease. Journal of Biological Chemistry, 2010. 285: 28796-805.

For a complete listing of Dr. Gustin's publications, search PubMed.

Research Interests

Virology, innate immunity, antiviral response

Research Summary

My lab aims to understand host-pathogen interactions that occur during infections with RNA viruses, such as rhinovirus and poliovirus. In addition to enhancing our understanding of pathogenesis, we hope to gain insights into mechanisms underlying such basic cellular processes as regulation of gene expression, nucleo-cytoplasmic trafficking and the antiviral response. We utilize a multidisciplinary approach incorporating cell and molecular biology, genetics, biochemistry and functional genomics.