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University of Arizona College of Medicine - Phoenix 475 North 5th Street, Phoenix, AZ 85004
Director
Professor, Tenure - Basic Medical Sciences
Director - Basic Medical Sciences
Faculty
Basic Medical Sciences; Basic Medical Sciences
Education
- Postdoctoral Fellowship: Metabolism, Johns Hopkins University, School of Medicine, 2009
- PhD: Physiology and Nutrition, University of Arkansas for Medical Sciences, 2007
- MS: Microbiology and Immunology, Third Military Medical University, 1994
- MD: Third Military Medical University, 1988
Research Interests
- Signal Transduction - Mitochondrial Dynamics - Metabolism in Obesity and Diabetes - Gene Regulation
Research Summary
His research focuses on glucose and lipid metabolism and the involvement of mitochondrial dynamics. Currently, his laboratory is working on (1) defining the molecular mechanisms of metformin’s effects on mitochondrial dynamics and respiration through AMPK activation; (2) investigating mechanisms leading to the paradoxical concurrence of insulin resistance and hepatic steatosis in obesity and type 2 diabetes; and (3) studying the mechanisms responsible for the mitochondrial expansion in neonates.