Contact:
University of Arizona College of Medicine - Phoenix 425 North 5th Street, Phoenix, AZ 85004
Assistant Professor, Tenure
Assistant Professor, Tenure - Basic Medical Sciences
Faculty
Basic Medical Sciences
Education
- Postdoctoral Fellowship: Cardiovascular Medicine and Radiology, Stanford University, Stanford Cardiovascular Institute, 2018
- PhD: Biomedical Engineering, Virginia Polytechnic Institute and State University, 2010
Publications
- Liu CW, Le HHT, Denaro P 3rd, Dai Z, Shao NY, Ong SG & Lee WH (2023). E-cigarettes induce dysregulation of autophagy leading to endothelial dysfunction in pulmonary arterial hypertension. Stem Cells., 01/14/2023 - Article, Refereed Journal -
- Jousma J, Han Z, Yan G, Nukala SB, Kwon Y, Le HHT, Li Y, Ong SB, Lee WH & Ong SG (2022). Alteration of the N6-methyladenosine epitranscriptomic profile in synthetic phthalate-treated human induced pluripotent stem cell-derived endothelial cells. Epigenomics. Vol. 14, 1139-1155., 10/2022 - Article, Refereed Journal -
- Nukala SB, Jousma J, Cho Y, Lee WH & Ong SG (2022). Long non-coding RNAs and microRNAs as crucial regulators in cardio-oncology. Cell & Bioscience. Vol. 12, 03/04/2022 - Article, Refereed Journal -
- Le HHT, Liu CW, Denaro P 3rd, Jousma J, Shao NY, Rahman I & Lee WH (2021). Genome-wide differential expression profiling of lncRNAs and mRNAs in human induced pluripotent stem cell-derived endothelial cells exposed to e-cigarette extract. Stem Cell Research & Therapy. Vol. 12, 12/04/2021 - Article, Refereed Journal -
- Jang HR, Cho HJ, Zhou Y, Shao NY, Lee K, Le HHT, Jeon J, Lee JE, Huh W, Ong SG, Lee WH & Kim YG (2021). Modeling uremic vasculopathy with induced pluripotent stem cell-derived endothelial cells as a drug screening system. Frontiers in Cell and Developmental Biology. Vol. 8, 01/12/2021 - Article, Refereed Journal -
More publications from this Faculty on
Research Interests
- Induced pluripotent stem cells (iPSCs) - Environmental Toxicology - Cardiovascular disease modeling
Research Summary
The Lee lab focuses on the use of human induced pluripotent stem cells (iPSCs) to study the interplay between environmental exposure and the development of cardiovascular diseases. We seek to achieve this understanding by various cellular, genetic and biochemical approaches coupled with patients’ data. A recent focus of our research is to develop a cellular model of human origin to assess potential cardiovascular susceptibility associated with radiation and e-cigarette/cigarette use.