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Associate research professor
Associate research professor
Faculty
Degrees
- MD: University of Aleppo, 1993
- PhD: CTS, University of Arizona, 2023
- MS: CTS/Perfusion, University of Arizona, 2019
Publications
- Sammani, Saad et al. “A novel S1P analogue/MLCK inhibitory peptide-encargoed nanocarrier to attenuate lung vascular leak.” American journal of respiratory cell and molecular biology, aanag069. 27 Mar. 2026, doi:10.1093/ajrcmb/aanag069
- Sammani, Saad et al. “eNAMPT Neutralization Preserves Lung Fluid Balance and Reduces Acute Renal Injury in Porcine Sepsis/VILI-Induced Inflammatory Lung Injury.” Frontiers in physiology vol. 13 916159. 22 Jun. 2022, doi:10.3389/fphys.2022.916159
- Bermudez, Tadeo et al. “eNAMPT neutralization reduces preclinical ARDS severity via rectified NFkB and Akt/mTORC2 signaling.” Scientific reports vol. 12,1 696. 13 Jan. 2022, doi:10.1038/s41598-021-04444-9
- Quijada, Hector et al. “Endothelial eNAMPT amplifies pre-clinical acute lung injury: efficacy of an eNAMPT-neutralising monoclonal antibody.” The European respiratory journal vol. 57,5 2002536. 6 May. 2021, doi:10.1183/13993003.02536-2020
- Sammani, Saad et al. “A sphingosine 1-phosphate 1 receptor agonist modulates brain death-induced neurogenic pulmonary injury.” American journal of respiratory cell and molecular biology vol. 45,5 (2011): 1022-7. doi:10.1165/rcmb.2010-0267OC
- Sammani, Saad et al. “Differential effects of sphingosine 1-phosphate receptors on airway and vascular barrier function in the murine lung.” American journal of respiratory cell and molecular biology vol. 43,4 (2010): 394-402. doi:10.1165/rcmb.2009-0223OC
Research Interests
- Pulmonary vascular permeability & endothelial barrier dysfunction
- In vivo models of endotoxin- and mechanical ventilation-induced acute lung injury in rodents and large animal models
- Biomarkers and therapeutic targets of acute respiratory distress syndrome (ARDS)