Dr. Aparna Sertil, PhD head shot

Contact Info

Building
AZ Biomedical Collaborative 1
Room Number
322
Assistant Professor
Faculty
College of Medicine Phx Basic Medical Sciences

Brief Bio

Education

  • Postdoctoral: Tumor Dormancy and Therapy Resistance, State University of New York – Albany, 2004 – 2008.
  • PhD: Albany Medical College, 2002.

Publications

For a complete listing of Dr. Sertil's publications, search PubMed.

Research Interests

Cancer, ER stress, microenvironment

Research Summary

My research is focused on elucidating the molecular mechanisms by which cues from the tumor microenvironment utilize the ER stress response and mTOR signaling to regulate tumor initiating “stem-cell” plasticity and tumor initiation; promote therapy resistance; and force actively proliferating tumor cells to enter dormancy. This will be important to both advance our understanding of tumorigenesis and metastasis, as well as identify new targets for development of therapeutics.