Departments of Basic Medical Sciences Seminar

Thursday, May 15, 2025 12:00 PM to 1:00 PM

A weekly lecture series covering diverse topics in the biomedical sciences

Presenter

Muralidhar Hegde, PhD, F.ABAP

Muralidhar Hegde, PhD, F.ABAP              

                   Everett E. and Randee K. Bernal Centennial Endowed Director of DNA Repair                  
Professor, Department of Neurosurgery
Director, Division of DNA Repair Research
Center for Neuroregeneration
Houston Methodist Research Institute
Houston Methodist, Houston, Texas, USA

Affiliate Faculty Member of Neuroscies, Weill Medical College, New York
Adjunct Faculty, Texas A & M University Graduate Program, College Station, Texas.

Deputy Chief Editor, Springer Journal ‘Metabloic Brain Disease’
Associate Editor, J Alzheimer’s Disease
Section Editor, International Journal of Molecular Sciences (IJMS)

Seminar Title

  • Targeting DNA Repair Pathways in Neurodegeneration: From Mechanisms to Therapeutics

Objectives

  1. Understand the Role of DNA Repair in Neurological Diseases:
    Participants will be able to explain how defects in DNA repair mechanisms contribute to the onset and progression of neurological disorders such as stroke, dementia, and motor neuron diseases.
  2. Explore Cutting-Edge Research Techniques in Genome Stability and Neurological research:
    Participants will gain insight into state-of-the-art molecular tools, including CRISPR/Cas9, patient-derived iPSCs, and mouse models, used to study genome damage and repair in the nervous system.
  3. Evaluate Mechanism-guided Therapeutic Strategies Targeting DNA Repair Pathways:
    Participants will be able to critically assess current and emerging therapeutic approaches that leverage DNA repair mechanisms to treat neurodegenerative diseases.

For additional information, please contact Lisa Dunk, 602-827-2188. This seminar will be hosted both via Zoom.

CME credit provided by the University of Arizona College of Medicine – Tucson.