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Are Weight-loss Drugs the Next Treatment for Obstructive Sleep Apnea?

Researchers reported that patients with obstructive sleep apnea who took tirzepatide, a GLP-1 inhibitor – one of the new class of weight-loss drugs – not only lost more weight than those taking a placebo but also improved on several measures of apnea severity and overall health. Joyce Lee-Iannotti, MD — clinical associate professor of Neurology, as well as the program director for the Sleep Medicine Fellowship and an associate clinical professor in the Division of Pulmonary, Critical Care and Sleep Medicine at the University of Arizona College of Medicine – Phoenix — said the researchers should have looked at cognitive outcomes, including biomarkers and tests of cognitive function. The cognitive impact of sleep apnea is also an important outcome measure to capture in interventional studies, she said

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Founded in 2007, the University of Arizona College of Medicine – Phoenix inspires and trains exemplary physicians, scientists and leaders to optimize health and health care in Arizona and beyond. By cultivating collaborative research locally and globally, the college accelerates discovery in a number of critical areas — including cancer, stroke, traumatic brain injury and cardiovascular disease. Championed as a student-centric campus, the college has graduated more than 900 physicians, all of whom received exceptional training from nine clinical partners and more than 2,700 diverse faculty members. As the anchor to the Phoenix Bioscience Core, which is projected to have an economic impact of $3.1 billion by 2025, the college prides itself on engaging with the community, fostering education, inclusion, access and advocacy.